Table 2.
Male and female group comparisons of blood pressure and total cholesterol at different time points
| Systolic BP(mmHg) | Control | Rosiglitazone | Diet | Insulin | Insulin + Orals | Metformin | Oral agents combination | Sulphonylurea |
|---|---|---|---|---|---|---|---|---|
|
Male | ||||||||
| N |
72 |
48 |
4 |
30 |
6 |
65 |
16 |
26 |
| Baseline |
119.1 ± 1.0 |
129.4 ± 1.0 |
114.4 ± 1.0 |
127.1 ± 1.0 |
139.1 ± 1.1 |
123.9 ± 1.0 |
139.3 ± 1.1 |
123.9 ± 1.0 |
| 6 months |
131.3 ± 1.0 |
131.3 ± 1.0 |
134.0 ± 1.2 |
125.0 ± 1.0 |
138.4 ± 1.0 |
124.1 ± 1.0 |
132.6 ± 1.0 |
126.2 ± 1.0 |
| 12 months |
130.7 ± 1.0 |
130.6 ± 1.1 |
- |
130.7 ± 1.1 |
124.0 ± 1.0* |
126.2 ± 1.0 |
133.2 ± 1.1* |
128.3 ± 1.0 |
|
Female | ||||||||
| N |
79 |
1 |
11 |
25 |
6 |
56 |
21 |
31 |
| Baseline |
114.0 ± 1.2 |
139.7 ± 1.0 |
127.9 ± 1.1 |
127.6 ± 1.0 |
121.4 ± 1.0 |
128.7 ± 1.1 |
130.4 ± 1.1 |
127.5 ± 1.0 |
| 6 months |
115.9 ± 1.1 |
- |
124.6 ± 1.1 |
122.9 ± 1.0 |
126.8 ± 1.0 |
126.2 ± 1.0 |
124.3 ± 1.0 |
132.1 ± 1.0 |
| 12 months |
116.4 ± 1.0 |
- |
132.7 ± 1.0 |
125.1 ± 1.1 |
129.1 ± 1.1 |
129.2 ± 1.0 |
124.3 ± 1.0* |
126.6 ± 1.0 |
|
Diastolic BP(mmHg) | ||||||||
|
Male | ||||||||
| Baseline |
75.4 ± 1.0 |
71.8 ± 1.0 |
72.2 ± 1.0 |
77.2 ± 1.0 |
74.5 ± 1.0 |
80.0 ± 1.0 |
74.0 ± 1.0 |
80.0 ± 1.0 |
| 6 months |
74.4 ± 1.0 |
80.6 ± 1.1 |
72.4 ± 1.0 |
79.0 ± 1.1 |
80.1 ± 1.1 |
78.2 ± 1.0 |
83.0 ± 1.1 |
83.5 ± 1.1 |
| 12 months |
74.1 ± 1.0 |
83.8 ± 1.1* |
- |
80.7 ± 1.1 |
87.5 ± 1.1* |
76.4 ± 1.0 |
87.4 ± 1.1* |
85.6 ± 1.1 |
|
Female | ||||||||
| Baseline |
74.0 ± 1.0 |
89.9 ± 1.1 |
80.4 ± 1.1 |
80.7 ± 1.1 |
76.5 ± 1.0 |
81.2 ± 1.0 |
80.6 ± 1.0 |
79.1 ± 1.0 |
| 6 months |
72.4 ± 1.0 |
- |
74.2 ± 1.0 |
76.8 ± 1.0 |
79.7 ± 1.0 |
78.2 ± 1.0 |
82.2 ± 1.0 |
72.5 ± 1.0 |
| 12 months |
72.2 ± 1.0 |
- |
74.7 ± 1.0 |
77.4 ± 1.0 |
77.9 ± 1.0 |
81.4 ± 1.0 |
77.3 ± 1.0 |
78.5 ± 1.0 |
|
Total cholesterol (mmol/l) | ||||||||
|
Male | ||||||||
| Baseline |
4.4 ± 0.02 |
4.7 ± 0.02 |
5.3 ± 0.08 |
4.9 ± 0.03 |
5.2 ± 0.06 |
5.3 ± 0.02 |
4.7 ± 0.04 |
5.3 ± 0.03 |
| 6 months |
4.6 ± 0.02 |
4.4 ± 0.02 |
7.2 ± 0.22 |
5.3 ± 0.04 |
5.0 ± 0.06 |
5.1 ± 0.03 |
4.5 ± 0.05 |
4.9 ± 0.04 |
| 12 months |
4.6 ± 0.03 |
4.0 ± 0.04 |
8.0 ± 0.22 |
4.6 ± 0.05 |
4.4 ± 0.12* |
4.9 ± 0.03 |
4.3 ± 0.08 |
5.0 ± 0.06 |
|
Female | ||||||||
| Baseline |
4.7 ± 0.02 |
4.6 ± 0.15 |
5.3 ± 0.04 |
5.3 ± 0.04 |
5.5 ± 0.06 |
5.2 ± 0.02 |
5.2 ± 0.03 |
5.3 ± 0.03 |
| 6 months |
4.7 ± 0.04 |
- |
5.1 ± 0.06 |
4.7 ± 0.04 |
5.1 ± 0.07 |
5.3 ± 0.02 |
5.2 ± 0.04 |
5.4 ± 0.03 |
| 12 months | 4.7 ± 0.03 | - | 5.4 ± 0.10 | 4.4 ± 0.04* | 4.4 ± 0.07* | 4.9 ± 0.03 | 4.7 ± 0.05 | 5.3 ± 0.04 |
Data represented by Mean ± standard error; ‘*’ Represents significant difference from the baseline. Level of significance is at p ≤ 0.05.