Table 3.
Male and female group comparisons of hdl-cholesterol, triglycerides and vitamin d at different time points
| HDL(mmol/l) | Control | Rosiglitazone | Diet | Insulin | Insulin + Orals | Metformin | Oral agents combination | Sulphonylurea |
|---|---|---|---|---|---|---|---|---|
|
Male | ||||||||
| Baseline |
0.57 ± 0.05 |
0.94 ± 0.06 |
0.99 ± 0.22 |
0.94 ± 0.08 |
0.81 ± 0.18 |
0.92 ± 0.06 |
0.93 ± 0.11 |
0.92 ± 0.09 |
| 6 months |
0.92 ± 0.09* |
1.0 ± 0.17 |
- |
1.0 ± 0.17 |
0.86 ± 0.26 |
0.81 ± 0.13 |
1.1 ± 0.26 |
1.0 ± 0.17 |
| 12 months |
0.94 ± 0.15* |
0.97 ± 0.13 |
- |
0.88 ± 0.12 |
1.1 ± 0.32* |
0.72 ± 0.19 |
0.88 ± 0.30 |
0.98 ± 0.28 |
|
Female | ||||||||
| Baseline |
0.76 ± 0.03 |
0.88 ± 0.22 |
1.1 ± 0.07 |
1.1 ± 0.04 |
1.0 ± 0.09 |
0.96 ± 0.03 |
1.0 ± 0.05 |
0.99 ± 0.04 |
| 6 months |
1.0 ± 0.06* |
- |
1.0 ± 0.16 |
1.0 ± 0.13 |
1.0 ± 0.15 |
1.0 ± 0.05 |
1.2 ± 0.13 |
1.0 ± 0.07 |
| 12 months |
0.99 ± 0.06* |
- |
|
1.2 ± 0.08 |
1.0 ± 0.17 |
1.1 ± 0.07 |
1.1 ± 0.10 |
1.1 ± 0.09 |
|
Triglycerides (mmol/l) | ||||||||
|
Male | ||||||||
| Baseline |
1.3 ± 0.03 |
2.3 ± 0.04 |
1.6 ± 0.16 |
1.7 ± 0.06 |
2.7 ± 0.13 |
2.1 ± 0.04 |
2.3 ± 0.08 |
2.2 ± 0.06 |
| 6 months |
1.2 ± 0.06 |
1.5 ± 0.04* |
1.1 ± 0.21 |
1.9 ± 0.09 |
1.7 ± 0.13* |
2.4 ± 0.07 |
1.6 ± 0.09* |
1.8 ± 0.07 |
| 12 months |
1.4 ± 0.07 |
1.5 ± 0.07* |
1.3 ± 0.22 |
1.7 ± 0.10 |
2.2 ± 0.12 |
2.3 ± 0.07 |
1.5 ± 0.12* |
2.0 ± 0.11 |
|
Female | ||||||||
| Baseline |
1.2 ± 0.03 |
2.5 ± 0.28 |
1.6 ± 0.08 |
1.9 ± 0.05 |
2.1 ± 0.11 |
1.7 ± 0.04 |
1.8 ± 0.06 |
1.9 ± 0.05 |
| 6 months |
1.3 ± 0.08 |
- |
1.5 ± 0.12 |
1.8 ± 0.07 |
2.1 ± 0.13 |
1.8 ± 0.05 |
1.9 ± 0.09 |
2.2 ± 0.06 |
| 12 months |
1.2 ± 0.06 |
- |
1.8 ± 0.20 |
1.3 ± 0.08 |
1.7 ± 0.13* |
1.6 ± 0.06 |
1.6 ± 0.10 |
2.0 ± 0.07 |
|
Vitamin D (nmol/l) | ||||||||
|
Male | ||||||||
| Baseline |
21.6 ± 1.0 |
33.7 ± 1.0 |
25.3 ± 1.0 |
34.9 ± 1.0 |
35.1 ± 1.0 |
35.7 ± 1.0 |
34.5 ± 1.0 |
34.5 ± 1.0 |
| 6 months |
30.8 ± 1.0* |
48.4 ± 1.0* |
39.1 ± 1.1* |
57.6 ± 1.1* |
52.8 ± 1.2* |
60.6 ± 1.1* |
49.6 ± 1.1* |
49.6 ± 1.1* |
| 12 months |
30.2 ± 1.1* |
50.4 ± 1.1* |
23.1 ± 1.0 |
50.1 ± 1.1* |
45.8 ± 1.1* |
54.5 ± 1.0* |
53.7 ± 1.0* |
53.1 ± .1.1* |
|
Female | ||||||||
| Baseline |
17.6 ± 1.0 |
19.2 ± 1.0 |
24.0 ± 1.0 |
29.6 ± 1.0 |
33.2 ± 1.0 |
34.7 ± 1.0 |
34.6 ± 1.1 |
40.4 ± 1.0 |
| 6 months |
24.2 ± 1.0 |
- |
33.3 ± 1.1 |
53.5 ± 1.1* |
59.1 ± 1.0* |
66.0 ± 1.2* |
42.1 ± 1.2* |
54.5 ± 1.1* |
| 12 months | 22.6 ± 1.0 | - | 29.2 ± 1.0 | 45.4 ± 1.1* | 49.1 ± 1.0* | 57.9 ± 1.1* | 42.9 ± 1.2* | 46.8 ± 1.0* |
Data represented by Mean ± standard error; ‘*’ Represents significant difference from the baseline. Level of significance is at p ≤ 0.05.