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. 2013 Aug 8;9:39. doi: 10.1186/1744-8069-9-39

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Copyright © 2013 Black et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Na_v1.7 expression in vasopressin- and oxytocin-producing magnocellular neurosecretory cells in supraoptic nucleus. Magnocellular neurosecretory neurons (MSN) of the supraoptic nucleus (SON) exhibit robust vasopressin and oxytocin immunolabeling (green). MSN of the SON display Na_v1.7 immunoreactivity (red). Double-immunocytochemical studies with antibodies to vasopressin or oxytocin and Na_v1.7 demonstrate that both peptide-producing cell-types exhibit co-localization (magenta) with Na_v1.7. Merged image of vasopressin or oxytocin with Na_v1.7 is presented as magenta to enhance visualization of co-localization.