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. 2013 Jul 4;8:164. doi: 10.1186/1748-717X-8-164

Table 2.

Summary of NTCP modeling studies of lung toxicity

Organ: Lung; End-point: Pneumonitis
Ref.
LKB model parameters
Notes
  n D50(Gy) m  
Emami et al. [39] / Burman et al. [23]
0.87
24.50
0.18
 
Kwa et al. [60]
1.00
30.50
0.30
 
Seppenwoolde et al. [38]
0.99
30.80
0.37
 
De Jeager et al. [24]*
1.00
34.10
0.45
 
De Jeager et al. [24]**
1.00
29.20
0.45
 
Ref.
Seriality model parameters
Notes
 
γ
D50(Gy)
s
 
Emami et al. [39] / Ågren-Cronqvist [40]
2.10
24.50
0.0061
 
Seppenwoolde et al. [38]
0.900
34.00
0.060
 
Gagliardi et al. [61] 0.966 30.10 0.012 lungs were considered as separate organs

Clinical data from Emami et al. [39], model fitting by Burman et al. [23].

* Tissue inhomogeneity correction: Equivalent-path.

** Tissue inhomogeneity correction: Convolution-superposition.

Clinical data from Emami et al. [39], model fitting by Ågren-Cronqvist [40].