Table 4.
Summary of NTCP modeling studies of rectal toxicity
|
Organ: Rectum; End-point: Late rectal bleeding | ||||
|---|---|---|---|---|
|
Ref. |
LKB model parameters |
Notes |
||
| n | D50(Gy) | m | ||
| Rancati et al. [62] |
0.23 |
81.90 |
0.19 |
solid rectum including filling |
| Rancati et al. [62] |
0.06 |
78.60 |
0.06 |
solid rectum including filling |
| Tucker et al. [45] |
0.08 |
78.00 |
0.14 |
solid rectum including filling |
| Peeters et al. [63] |
0.13 |
80.70 |
0.14 |
rectal wall |
| Söhn et al. [47] |
0.08 |
78.40 |
0.11 |
rectal wall |
| Rancati et al. [46] |
0.085 |
97.70 |
0.27 |
solid rectum including filling |
|
Ref. |
Seriality model parameters |
Notes |
||
| |
γ |
D50(Gy) |
s |
|
| Rancati et al. [62] | 1.69 | 83.10 | 0.49 | solid rectum including filling |