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In vivo effect of leukotoxin in rats. Leukotoxin was injected intravenously (0.34 mg/kg) or subcutaneously (0.80 mg/kg) into Sprague–Dawley rats, blood samples were withdrawn at the various times noted, and CBC analyses were performed. Data are given as mean ± SE (n = 4). No significant changes in WBC counts were noted after injection of the vehicle control (data not shown). *, Value significantly (P ≤ 0.05) different from the corresponding preinjection value.
