Table 1.
Clinical characteristics of participants (mean ± SD and %)
| Men (n=432) | Women (n=456) | All subjects (n=888) | |
|---|---|---|---|
| BMI (kg/m2) |
27.1±3.6 |
27.0±4.8 |
27.0 ± 4.3 |
| Current smokers |
10 |
11 |
10 |
| Ex-smokers |
48 |
35 |
41 |
| Never-smokers |
42 |
54 |
48 |
| Hypertension |
31 |
32 |
32 |
| Myocardial infarction |
10 |
3 |
7 |
| Stroke |
4 |
2 |
3 |
| FEV1 (L) |
2.88±0.62 |
2.02±0.41 |
2.44±0.68 |
| FEV1 % predicted |
96±20 |
101±19 |
99±20 |
| FVC (L) |
3.85±0.70 |
2.60±0.49 |
3.21±0.87 |
| FVC % predicted |
95±16 |
108±18 |
102±18 |
| Leukocyte count (x109/L) |
5.8±1.5 |
5.5±1.4 |
5.7±1.5 |
| CRP (mg/L) |
1.2 (1.1-1.4) |
1.4 (1.3-1.5) |
1.3 (1.2-1.4) |
| MCP-1 (ng/L) |
368 (355–381) |
366 (353–380) |
367 (358–377) |
| IL-2 (ng/L) |
4.6 (4.2-4.9) |
5.0 (4.6-5.4) |
4.8 (4.5-5.0) |
| IL-6 (ng/L) |
7.0 (6.0-8.1) |
5.8 (5.0-6.8) |
6.4 (5.7-7.1) |
| IL-8 (ng/L) |
6.3 (5.9-6.7) |
6.6 (6.2-7.0) |
6.4 (6.2-6.7) |
| INF γ (ng/L) |
1.8 (1.7-1.9) |
1.9 (1.8-2.0) |
1.8 (1.8-1.9) |
| TNFα (ng/L) |
4.2 (4.0-4.4) |
4.0 (3.8-4.2) |
4.1 (3.9-4.2) |
| EGF (ng/L) |
20.6 (18.7-22.8) |
24.2 (22.0-26.5) |
22.4 (20.9-23.9) |
| VEGF (ng/L) |
161 (150–174) |
191 (177–206) |
176 (167–185) |
| VCAM-1 (μg/L) |
540 (529–552) |
508 (497–520) |
524 (515–532) |
| ICAM-1 (μg/L) |
346 (339–354) |
354 (345–362) |
350 (345–356) |
| E-selectin (μg/L) |
15.0 (14.5-15.5) |
13.9 (13.3-14.4) |
14.4 (14.0-14.8) |
| P-selectin (μg/L) |
99.2 (96.0-102) |
95.7 (93.2-98.3) |
97.4 (95.4-99.5) |
| L-selectin (μg/L) | 688 (676–700) | 731 (718–744) | 709 (701–718) |