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. 2001 Jul 10;98(15):8750–8755. doi: 10.1073/pnas.151028698

Figure 4.

Figure 4

Modulated DCs fail to induce allogeneic T-cell responses. Proliferative allogeneic T-cell responses to DCs modulated by anti-CD36 mAb (A), by anti-CD51 mAb (B), or by apoptotic cells (C). The stimulator DCs were: immature DC alone (filled squares) or matured with LPS (open squares); DCs exposed to isotype-control Igs and then matured with LPS (open diamond); DCs exposed to anti-CD36 in (A), anti-CD51 mAb in (B) or apoptotic cells in (C) alone (filled triangle) or matured with LPS (open triangle). Shown is one representative experiment of at least three. Stimulation of T cells by modulated DCs was significantly reduced (P < 0.01) compared with mature DCs.