Figure 6.
Effect of modulating agents on LPS-induced secretion of TNF-α, IL-12p70, and IL -10 by DCs. Cytokine secretion over 24 h by immature DCs (DC) and LPS-matured DCs alone (DC LPS) or exposed to anti-CD36 (DC anti-CD36 LPS) or isotype control (DC isoM LPS) mAb, apoptotic cells (DC apo-DC LPS), or iRBC (DC iRBC LPS). The cytokine levels in culture medium alone (medium) or supernatants from apoptotic cells alone (apo-DC) are also indicated. Shown are the mean and SD of cytokine secretion by DCs and controls exposed to mAbs (n = 13), to apoptotic cells (n = 7), or to iRBC (n = 4). ns, not significant. **, P < 0.01.