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. 2013 Aug 7;10:53. doi: 10.1186/1743-7075-10-53

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Copyright © 2013 Swaid et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effect of acetic acid and oral glutamine on crypt cell proliferation. 5-BrdU incorporation into proliferating jejunal and ileal crypt cells was detected with a goat anti-BrdU antibody. The representative sections (on the right side) demonstrate that cell proliferation decreased following AA-damage compared to control animals. Following administration of oral glutamine, AA-rats demonstrated a marked increase in a number of proliferating cells compared to AA non-treated animals. Values are mean ± SEM. CONTR-control; AA- acetic acid; GLN- glutamine. * P < 0.05 vs CONTR rats, † P < 0.05 AA-GLN vs AA rats.