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. Author manuscript; available in PMC: 2013 Aug 23.
Published in final edited form as: J Am Soc Hypertens. 2011 Oct 22;6(1):66–72. doi: 10.1016/j.jash.2011.09.001

Table 3.

Change in computed ambulatory blood pressure parameters after 3 weeks of AM or PM dosed nebivolol

Parameter AM Nebivolol (mm Hg) PM Nebivolol (mm Hg) P Value (AM vs. Baseline) P Value (PM vs. Baseline) P Value (AM vs. PM Nebivolol)
Trough MSBPS −7.54 ± 18.23 −11.08 ± 31.41 .014 .034 .497
Trough MDBPS −3.64 ± 15.33 −4.03 ± 13.70 .146 .074 .879
Prewaking SBP −1.62 ± 18.32 −8.64 ± 26.46 .585 .048 .137
Prewaking DBP 3.08 ± 14.29 −1.41 ± 10.88 .187 .423 .022
Nocturnal SBP fall −9.69 ± 20.54 −4.69 ± 25.29 .005 .254 .130
Nocturnal DBP fall −4.49 ± 15.20 −3.23 ± 17.32 .073 .251 .623
Nocturnal SBP dip −2.07% ± 9.56% −0.12% ± 8.25% .893 .928 .974
Nocturnal DBP dip −0.6% ± 11.1% −0.48% ± 9.2% .726 .751 .986

AM, morning; DBP, diastolic blood pressure; MDBPS, mean diastolic blood pressure surge; PM, evening; MSBPS, mean systolic blood pressure surge; SBP, systolic blood pressure.

All values (except prewaking DBP for AM nebivolol) reflect a decline from baseline levels.