Table 3.
Parameter | AM Nebivolol (mm Hg) | PM Nebivolol (mm Hg) | P Value (AM vs. Baseline) | P Value (PM vs. Baseline) | P Value (AM vs. PM Nebivolol) |
---|---|---|---|---|---|
Trough MSBPS | −7.54 ± 18.23 | −11.08 ± 31.41 | .014 | .034 | .497 |
Trough MDBPS | −3.64 ± 15.33 | −4.03 ± 13.70 | .146 | .074 | .879 |
Prewaking SBP | −1.62 ± 18.32 | −8.64 ± 26.46 | .585 | .048 | .137 |
Prewaking DBP | 3.08 ± 14.29 | −1.41 ± 10.88 | .187 | .423 | .022 |
Nocturnal SBP fall | −9.69 ± 20.54 | −4.69 ± 25.29 | .005 | .254 | .130 |
Nocturnal DBP fall | −4.49 ± 15.20 | −3.23 ± 17.32 | .073 | .251 | .623 |
Nocturnal SBP dip | −2.07% ± 9.56% | −0.12% ± 8.25% | .893 | .928 | .974 |
Nocturnal DBP dip | −0.6% ± 11.1% | −0.48% ± 9.2% | .726 | .751 | .986 |
AM, morning; DBP, diastolic blood pressure; MDBPS, mean diastolic blood pressure surge; PM, evening; MSBPS, mean systolic blood pressure surge; SBP, systolic blood pressure.
All values (except prewaking DBP for AM nebivolol) reflect a decline from baseline levels.