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. Author manuscript; available in PMC: 2014 Feb 7.
Published in final edited form as: Lab Chip. 2013 Feb 7;13(3):340–348. doi: 10.1039/c2lc41117b

Fig. 2.

Fig. 2

Cell invasion phases. a) The dynamics of a cell invading across subnucleus barriers can be segmented into 4 phases, as shown in the timelapse image stack (17 min/frame). The cell slows down as it reaches the barrier (phase 1), the cell body starts permeating into the barrier (phase 2), the cell pauses or otherwise stops monotonic forward motion (phase 3), and the cell resumes monotonic forward motion and exits the barrier (phase 4). b) The average time constants for these phases are measured for invasions across the subnucleus barriers SNB10 (n = 62) and SNB60 (n = 20), where n is the number of invasion events observed. The width of the larger channel is 15 μm.