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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Environ Mol Mutagen. 2013 Feb 26;54(3):195–203. doi: 10.1002/em.21763

Figure 1. Decreasing SEPP1 Methylation Levels with Hair Hg among Males.

Figure 1

Mean % methylation of four CpG sites in SEPP1 is plotted against natural log-transformed hair Hg levels (μg/g) with gender stratification for A) all MDA subjects (n=57 males, 59 females) and B) dentists only (n=53 males, 12 females). SEPP1 is significantly hypomethylated with increasing hair Hg among males (Pearson r= −0.28, p=0.04), and the trend persists when excluding non-dentist males (r= −0.22, p=0.12). This trend is not apparent among all females (r= 0.12, p=0.37) or female dentists (r= 0.36, p=0.25).