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Pathohistology of Morphea
| Early Phase | Sclerotic Stage |
|---|---|
| Oedematous swelling of collagen fibres | Homogenised collagen fibre bundle |
| Cell infiltration of lymphocytes, eosinophils and plasma cells | Decrease in strength of fibrils |
| Reduction in cell infiltrates | |
| Slit-like narrowing of vessels | |
| Loss of accessory structures of the skin | |
| Hyaline sclerotic transformation of corium |
