Table 2.
Pathohistology of Acrodermatitis Chronica Atrophicans
| Inflammatory Stage | Atrophic Stage |
|---|---|
| Oedematous swelling of hyalinised collagen fibres | Atrophy with disappearance of elastic fibres |
| Undulating or ribbon-like perivascular lymphocytic infiltrates | Nests of Borrelia can be found in the collagen fibre bundles |
| Subepidermal haemorrhagic blisters due to infiltration of blood | |
| Deposit of IgM, IgG, IgA, complement and fibrin |