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Pathohistology of Lichen Sclerosus et Atrophicus
| Initial Phase | Late Phase |
|---|---|
| Oedematous swelling of hyalinised collagen fibres | Atrophy with disappearance of elastic fibres |
| Undulating or ribbon-like perivascular lymphocytic infiltrates | Foci of Bb can be found in the collagen fibre bundles |
| Subepidermal haemorrhagic blisters due to infiltration of blood | |
| Deposit of IgM, IgG, IgA, complement and fibrin |
