Table 1.
Top 30 frequent annotated functions of homologous protein clusters in Fav1
|
Top frequent GO-annotated homologous protein clusters in Fav1 | ||
|---|---|---|
| Go categories/Description | Count | Percentage |
| Total clusters |
7,187 |
|
| Total (GO-annotated) |
4,677 |
65.1% |
|
Molecular function |
3,477 |
48.37% |
| 1-Nucleic acid binding |
241 |
5.15% |
| 2-Protein kinase activity |
218 |
4.66% |
| 3-DNA binding |
208 |
4.45% |
| 4-Catalytic activity |
173 |
3.70% |
| 5-Calcium ion binding |
158 |
3.38% |
| 6-ATP binding |
129 |
2.76% |
| 7-Protein binding |
119 |
2.54% |
| 8-GTP binding |
114 |
2.44% |
| 9-Transporter activity |
96 |
2.05% |
| 10-Structural constituent of ribosome |
82 |
1.75% |
|
Biological process |
776 |
16.59% |
| 1-Metabolism |
122 |
2.61% |
| 2-Electron transport |
88 |
1.88% |
| 3-Intracellular signaling cascade |
54 |
1.15% |
| 4-Proteolysis and peptidolysis |
48 |
1.03% |
| 5-Protein folding |
47 |
1.00% |
| 6-Protein modification |
31 |
0.66% |
| 7-Cell adhesion |
29 |
0.62% |
| 8-Intracellular protein transport |
26 |
0.56% |
| 9-Carbohydrate metabolism |
21 |
0.45% |
| 10-Regulation of cell cycle |
18 |
0.38% |
|
Cellular component |
424 |
6% |
| 1-Ubiquitin ligase complex |
68 |
1.45% |
| 2-Integral to membrane |
58 |
1.24% |
| 3-Membrane |
58 |
1.24% |
| 4-Nucleus |
46 |
0.98% |
| 5-Intracellular |
41 |
0.88% |
| 6-Cytoplasm |
26 |
0.56% |
| 7-Cytoskeleton |
24 |
0.51% |
| 8-Nucleosome |
16 |
0.34% |
| 9-Chromatin |
10 |
0.21% |
| 10-Extracellular region | 8 | 0.17% |
Top 30 high frequent annotated homologous protein clusters under cellular component, molecular function and biological processes. Full annotation included in Additional file 9: File S8.