Table 3.
The distributions of haplotypes in ASD and controls
| Haplotype | Cases (frequency) | Controls (frequency) | Chi2 | Fisher's P | Pearson's P | Odds ratio (95%CI) | |
|---|---|---|---|---|---|---|---|
| 1 |
A C A C A A G G T |
8.84 (0.012) |
28.20 (0.036) |
7.081 |
0.007814a |
0.007806a |
0.367 (0.170 to 0.790) |
| 2 |
C C A C C A A C C |
41.17 (0.057) |
63.13 (0.080) |
1.548 |
0.213443 |
0.213365 |
0.768 (0.506 to 1.165) |
| 3 |
C C A C C A A C T |
84.15 (0.117) |
60.19 (0.076) |
11.981 |
0.000542a |
0.000541a |
1.880 (1.310 to 2.698) |
| 4 |
C C A C C A G G C |
12.99 (0.018) |
26.04 (0.033) |
2.331 |
0.126865 |
0.126793 |
0.592 (0.300 to 1.168) |
| 5 |
C C A C C A G G T |
86.66 (0.121) |
89.80 (0.114) |
1.380 |
0.240147 |
0.240071 |
1.218 (0.876 to 1.694) |
| 6 |
C C A T C A A C T |
27.74 (0.039) |
25.95 (0.033) |
0.973 |
0.324045 |
0.323985 |
1.319 (0.759 to 2.292) |
| 7 |
C G G C A A A C T |
31.96 (0.045) |
32.97 (0.042) |
0.465 |
0.495147 |
0.495131 |
1.192 (0.719 to 1.976) |
| 8 |
C G G C A A G G C |
30.14 (0.042) |
45.29 (0.057) |
0.902 |
0.342270 |
0.342214 |
0.792 (0.490 to 1.282) |
| 9 |
C G G C A A G G T |
60.91 (0.085) |
81.38 (0.103) |
0.381 |
0.537097 |
0.537090 |
0.892 (0.622 to 1.281) |
| 10 | C G G C A G G C T | 19.59 (0.027) | 37.66 (0.048) | 2.960 | 0.085418 | 0.085359 | 0.613 (0.349 to 1.076) |
ASD, autistic spectrum disorders; Global result: total control = 788.0, total case = 718.0; global chi2 is 26.804893 while df = 9 (frequency < 0.03 in both control and case has been dropped). Fisher's P value is 0.001537. Pearson's P value is 0.001507. Note: aP ≤ value 0.05.