Table 2.
Chi-square test and Fisher’s exact test of relationship between DEK over expression and the clinicopathological features in colorectal cancers
| Characteristic | No. of cases | Strongly positive cases (%) | OR (95% CI) | P value |
|---|---|---|---|---|
|
Gender |
|
|
2.461 (0.924-6.556) |
0.067 |
| Male |
87 |
45 (51.72%) |
|
|
| Female |
22 |
8 (36.36%) |
|
|
|
Age (years old) |
|
|
1.298 (0.611-2.756) |
0.497 |
| ≥49 |
53 |
24 (45.28%) |
|
|
| <49 |
56 |
29 (51.79%) |
|
|
|
Tumor size (cm) |
|
|
2.353 (1.086-5.101) |
0.029 |
| ≤5 |
61 |
24 (39.34%) |
|
|
| >5 |
48 |
29 (60.42%) |
|
|
|
Location |
|
|
0.900 (0.424-1.910) |
0.784 |
| Colonic & ileocecal |
57 |
27 (47.37%) |
|
|
| Rectal |
52 |
26 (50.00%) |
|
|
|
Differentiation |
|
|
2.824 (1.291-6.177) |
0.009 |
| Well diff. |
49 |
17 (34.69%) |
|
|
| Poorly & mod. diff. |
60 |
36 (60.00%) |
|
|
|
Lymph node metastasis |
|
|
2.975 (1.360-6.509) |
0.006 |
| - |
60 |
22 (36.67%) |
|
|
| + |
49 |
31 (63.27%) |
|
|
|
Serosal invasion |
|
|
2.353 (1.072-5.163) |
0.031 |
| - |
57 |
17 (29.82%) |
|
|
| + |
52 |
26 (50.00%) |
|
|
|
Stage |
|
|
2.744 (1.261-5.971) |
0.010 |
| I-IIA |
59 |
22 (37.29%) |
|
|
| IIB-IIIC |
50 |
31 (62.00%) |
|
|
|
CEA |
|
|
0.610 (0.273-1.362) |
0.228 |
| Normal |
37 |
15 (40.54%) |
|
|
| Increased | 72 | 38 (52.78%) |