Table 2.

Summary statistics for ordered subset linkage analysis

Chr	Linkage peak (cM)a	New lodb	Old lodc	Delta lodd	No. of families	Admixture Range, Mean, Variancee	Empirical P-value for changef	NPL pointwise P valueg	NPL genomewide P valueh
4	180.1	4.24	0.28	3.96	44	[0.858, 0.996], 0.92, 0.0013	0.0001	<0.00001	0.008
12	6.0	3.07	0.49	2.58	49	[0.443, 0.813], 0.73, 0.0079	0.021	0.00009	0.052
15	34.8	2.72	0.33	2.39	40	[0.443, 0.801], 0.71, 0.0080	0.026	0.0002	0.11
22	45.9	3.23	0.35	2.88	33	[0.885, 0.996], 0.93, 0.00085	0.0069	0.00006	0.041

^alocation of maximum lod score, maximized over all loci and ordered subsets.

^bmaximum lod score, maximized over all loci and ordered subsets.

^cmaximum lod score, maximized over all loci in the overall families.

^d(New lod) – (Old lod).

^erange, mean and variance of African ancestry proportion.

^fempirical P value of increased evidence for linkage obtained by 10000 times permutation test.

^gNPL (non-parametric linkage analysis) P value obtained by performing NPL analysis using the subsets of families identified from OSA.

^hgenomewide empirical P value obtained by 1000 times simulations using the subsets of families identified from OSA.