Table 2.
Local thermal hyperaemia, SNP- and PCH-induced vasodilation in healthy controls and patients with type 1 diabetes
| Controls | Patients | p | |
|---|---|---|---|
| ARR (cut-off: 4.3 [raPU*min]) |
|
|
|
| Median (range) |
9.05 (0.40-64.9) |
7.22 (0.62-27.6) |
0.003 |
| Below cut-off |
10/102 |
18/68 (26.5%) |
|
| AUCheat(cut-off:153 [raPU*min]) |
|
|
|
| Median (range) |
399 (45–1053) |
301 (0–988) |
0.006 |
| Below cut-off |
10/102 |
16/68 (23.5%) |
|
| maxSkBFheat(cut-off:5.9 [raPU]) |
|
|
|
| Median (range) |
15.4 (1–40) |
10.8 (1–36) |
0.007 |
| bBelow cut-off |
10/102 |
12/68 (17.6%) |
|
| AUCSNP (cut-off:18.6 [raPU*min]) |
|
|
|
| Median (range) |
64.6 (0–244) |
41.7 (0–215) |
<0.001 |
| Below cut-off |
10/102 |
17/68 (25%) |
|
| maxSkBFSNF (cut-off:3.0 [raPU]) |
|
|
|
| Median (range) |
12.1 (1–47.8) |
7.4 (1–30.9) |
<0.001 |
| Below cut-off |
10/102 |
14/68 (20.6%) |
|
| AUCPCH (cut-off:6.6 [raPU*min]) |
|
|
|
| Median (range) |
30.6 (0.158) |
27.9 (0–175) |
0.427 |
| Below cut-off |
10/102 |
8/68 (11.8%) |
|
| maxSkBFPCH (cut-off:2.1 [raPU]) |
|
|
|
| Median (range) |
8.0 (1–45.6) |
7.0 (1–35.4) |
0.100 |
| Below cut-off | 10/102 | 10/68 (14.7&) |
Per parameter, median and range as well as the number of individuals with an inadequately low response to exogenous stimulation of skin microcirculation are given.