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Schematic representation of an in vitro model for iodine-125 seed irradiation. The model was consisted of a lower seed plate layer and an upper-cell culture plate layer. In the seed plate, 14 seeds with the same activity were equally spaced within recesses around a 35-mm diameter circumference. For the cell-culture plate, similar recesses were made around a 35-mm diameter circumference. The height between the seed plate and the bottom of the Petri dish was 12 mm.
