Table 4.
Univariate associations between cardiac involvement and clinical data in 210 patients with ankylosing spondylitis
| |
PQ interval |
|
QRS interval |
|
AVB IVCD |
|
AVB IVCDx |
|
|---|---|---|---|---|---|---|---|---|
| Beta (95% CI) | p | Beta (95% CI) | p | OR (95% CI) | p | OR (95% CI) | p | |
| Age |
0.47 ( 0.19,0.74) |
.001 |
0.10 (−0.04,0.25) |
.17 |
1.088 (1.040,1.138) |
.0003 |
1.070 (1.033,1.109) |
.0002 |
| Male gender |
15.3 (8.2,22.4) |
<.0001 |
10.8 (7.3,14.3) |
<.0001 |
8.28 (1.88,36.53) |
.005 |
4.70 (1.73,12.80) |
.002 |
| Age spt onset |
0.27 (−0.12,0.66) |
.17 |
0.12 (−0.08,0.32) |
.24 |
1.002 (0.956,1.051) |
.92 |
1.015 (0.976,1.055) |
.46 |
| Symptom dur. |
0.38 ( 0.09,0.67) |
.01 |
0.02 (−0.13,0.17) |
.79 |
1.069 (1.030,1.111) |
.0005 |
1.055 (1.023,1.088) |
.0007 |
| BASDAI |
−0.16 (−0.88,1.56) |
.86 |
−0.93 (−1.78,-0.09) |
.03 |
0.993 (0.801,1.232) |
.95 |
0.997 (0.832,1.194) |
.97 |
| BASFI |
1.68 (−0.09,3.46) |
.06 |
−0.44 (−1.33,0.45) |
.33 |
1.207 (0.984,1.479) |
.07 |
1.239 (1.041,1.474) |
.02 |
| BASMI |
3.42 ( 1.12,5.72) |
.004 |
0.24 (−0.95,1.44) |
.69 |
1.593 (1.224,2.074) |
.0005 |
1.566 (1.241,1.975) |
.0002 |
| Length |
−0.61 ( 0.24,0.97) |
.001 |
0.52 ( 0.35,0.70) |
<.0001 |
1.060 (1.009,1.114) |
.02 |
1.048 (1.006,1.092) |
.02 |
| Weight |
0.52 ( 0.31,0.74) |
<.0001 |
0.29 ( 0.18,0.40) |
<.0001 |
1.039 (1.012,1.067) |
.005 |
1.051 (1.025,1.077) |
<.0001 |
| BMI |
0.66 (−0.14,1.46) |
.11 |
0.40 (−0.01,0.81) |
.05 |
0.956 (0.857,1.068) |
.43 |
1.011 (0.931,1.097) |
.80 |
| Hb |
0.57 ( 0.29,0.85) |
<.0001 |
0.27 ( 0.13,0.42) |
.0002 |
1.027 (0.989,1.066) |
.17 |
1.038 (1.005,1.073) |
.02 |
| ESR |
−0.09 (−0.36,0.18) |
.49 |
−0.10 (−0.24,0.03) |
.14 |
1.007 (0.977,1.038) |
.65 |
0.991 (0.959,1.023) |
.56 |
| CRP |
−0.04 (−0.41,0.33) |
.82 |
−0.04 (−0.22,0.15) |
.69 |
1.025 (0.994,1.058) |
.12 |
1.021 (0.992,1.052) |
.16 |
| WBC |
−1.79 (−3.51,-0.07) |
.04 |
−0.56 (−1.43,0.32) |
.21 |
0.977 (0.787,1.213) |
.83 |
0.863 (0.700,1.063) |
.17 |
| PLT |
−0.05 (−0.10,-0.00) |
.05 |
−0.01 (−0.04,0.01) |
.37 |
0.998 (0.992,1.004) |
.58 |
0.995 (0.990,1.001) |
.10 |
| B27 alleles | 6.2 (−4.8,17.2) | .27 | −0.2 (−5.9,5.4) | .93 | 3.21 (0.41,24.95) | .26 | 2.37 (0.53,10.55) | .26 |
AVB IVCD denotes atrio-ventricular and intra-ventricular conduction disturbances according to standard (conservative) criteria (n = 21).
AVB IVCDx denotes such disturbances according to less conservative criteria (n==31) for comparison with ref. [13].
Abbreviations: PQ interval = duration from P-wave to QRS complex; QRS interval = duration of QRS complex; AVB atrio-ventricular Block; IVCD intra-ventricular conduction disturbances: BASDAI Bath Ankylosing Spondylitis Disease Activity Index; BASFI Bath Ankylosing Spondylitis Functional Index; BASMI Bath Ankylosing Spondylitis Metrology Index; BMI Body Mass Index; Hb Hemoglobin (g/L); ESR Erythrocyte Sedimentation Rate (mm/h); CRP C-reactive protein (mg/L); WBC White Blood Cells (×109/L); PLT Platelet Count (×109/L).
Beta regression coefficient; CI confidence interval; OR = odds ratio.
Univariate associations (univariate linear regression and logistic regression).