Table 1.
Mean (± SD, n = 6) flunixin meglumine plasma concentrations (ng ml-1) after a single intravenous (IV), intramuscular (IM) or oral (PO) administration in gilts
|
Administration route | ||||||
|---|---|---|---|---|---|---|
| Time (hours) | IV | ±SD | IM | ±SD | PO | ±SD |
|
0.05 |
21695.1 |
4036.6 |
- |
- |
- |
- |
|
0.10 |
18615.7 |
3638.1 |
- |
- |
- |
- |
|
0.17 |
22819.35 |
17414.12 |
2830.6 |
1237.3 |
- |
- |
|
0.25 |
- |
- |
- |
- |
537.4 |
231.4 |
|
0.33 |
10018.9 |
1896.4 |
3100.0 |
1224.0 |
- |
- |
|
0.5 |
8989.7 |
3304.1 |
- |
- |
987.8 |
432.9 |
|
0.67 |
- |
- |
3258.6 |
1565.2 |
- |
- |
|
1.0 |
3358.1 |
829.9 |
2761.1 |
850.1 |
786.2 |
385.1 |
|
2.0 |
2005.4 |
663.1 |
2264.1 |
380.4 |
869.7 |
337.2 |
|
4.0 |
908.9 |
254.5 |
1194.8 |
574.3 |
440.2 |
204.1 |
|
8.0 |
407.1 |
87.6 |
593.2 |
327.0 |
173.7 |
114.7 |
|
12.0 |
- |
- |
- |
- |
76.2 |
61.4 |
|
16.0 |
93.8 |
57.4 |
176.1 |
87.2 |
46.7 |
38.8 |
|
24.0 |
32.8 |
20.4 |
66.2 |
30.2 |
16.7 |
16.5 |
|
36.0 |
10.8 |
7.28 |
28.4 |
17.2 |
6.15 |
4.08 |
| 48.0 | 2.68 | 1.80 | 10.2 | 8.8 | 2.2 | 1.1 |
Time (hours) began once drug was administered.