Table 1.
Clinical and hormonal features of women with PCOS and controls
| Characteristic | Control (n = 14) | PCOS (n = 22) | p | p* |
|---|---|---|---|---|
|
Age (years) |
25.4 ± 2.4 |
23.9 ± 6.2 |
0.334 |
0.501 |
|
BMI (kg/m2) |
26.9 ± 5.5 |
30.8 ± 5.9 |
0.058 |
|
|
Waist circumference (cm) |
85.5 ± 9.8 |
90.9 ± 13.7 |
0.321 |
0.166 |
|
WHR |
0.78 ± 0.06 |
0.83 ± 0.09 |
0.120 |
0.079 |
|
Ferriman-Gallwey score |
1 (0–3) |
9 (8–14) |
0.003 |
0.003 |
|
Systolic BP (mmHg) |
111 ± 4 |
117 ± 16 |
0.096 |
0.291 |
|
Diastolic BP (mmHg) |
68 ± 6 |
75 ± 12 |
0.178 |
0.187 |
|
Glucose, fasting (mg/dL) |
87 ± 6 |
88 ± 6 |
0.555 |
0.597 |
|
Glucose, 2 h (mg/dL) |
89 ± 13 |
117 ± 25 |
0.007 |
0.006 |
|
Insulin, fasting (μIU/mL) |
7.8 (4.3-11.2) |
12 (8–19) |
0.012 |
0.089 |
|
Insulin, 2 h (μIU/mL) |
56.6 (36.8-94.7) |
101 (46–175) |
0.049 |
0.110 |
|
HOMA-IR |
1.8 (1.3-2.8) |
2.6 (1.8-4.2) |
0.083 |
0.100 |
|
Triglycerides (mg/dL) |
54 (40–72) |
77 (48–119) |
0.135 |
0.441 |
|
Total cholesterol (mg/dL) |
144 ± 35 |
178 ± 40 |
0.013 |
0.026 |
|
HDL cholesterol (mg/dL) |
48 ± 15 |
53 ± 9 |
0.272 |
0.277 |
|
LDL cholesterol (mg/dL) |
83 ± 27 |
109 ± 35 |
0.024 |
0.036 |
|
LH (mIU/mL) |
6.0 (4.0-7.6) |
10.9 (6.5-18.6) |
0.011 |
0.020 |
|
SHBG (nmol/L) |
44.9 (35.3-59.3) |
34.9 (18.4-47.8) |
0.173 |
0.360 |
|
Total T (ng/mL) |
0.60 (0.47-0.72) |
1.26 (0.91-1.43) |
<0.001 |
0.001 |
| FAI | 4.7 (3.8-6.1) | 9.4 (6.8-21.3) | 0.001 | 0.101 |
Values are expressed as mean ± SD or median (interquartile range). Statistical differences by unpaired two-tailed Student’s t-test or Mann–Whitney U test. BMI body mass index, BP blood pressure, FAI free androgen index, HDL high-density lipoprotein, HOMA-IR homeostasis model assessment, LDL low-density lipoprotein, LH luteinizing hormone, PCOS polycystic ovary syndrome, SHBG sex hormone-binding globulin, T testosterone, WHR waist to hip ratio. *Adjusted for BMI (linear regression).