FIG. 5.
FACS analysis of wild-type and knockout strains of N. meningitidis serogroup B labeled with homologous antiserum to rLP2086. (A) Labeling of three wild-type strains with homologous rLP2086 antiserum, with the negative control (week 0) shown as the light gray histogram and the positive antiserum (week 6) shown as a bold unfilled histogram. (B) Labeling of the knockout strains with the same antiserum and the same labels as for panel A, with a light gray histogram for the negative control and a bold line for the anti-rLP2086 serum. (C) Labeling of wild-type (dark gray, filled histogram) and knockout strains (bold unfilled histogram) with the homologous PorA monoclonal antibody specific for each serosubtype.