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. 2013 Aug 2;12:270. doi: 10.1186/1475-2875-12-270

Table 4.

Statistical value of clinical signs, association of clinical signs and malaria tests (QBC and HRP2-based RDT) for the diagnosis of malaria, according to the results of the thick and thin Giemsa-stained blood films, considered to be the gold standard method (with 95% confidence intervals for sensibility and specificity)

  Sensibility Specificity Positive predictive value Negative predictive value
Isolated fever
78.3%
71.3%
44.3%
91.9%
[68.5 – 88.0]
[65.6 – 77.1]
Fever present on examination
31.9%
85.2%
38.6%
81.1%
[20.9 – 42.9]
[80.7 – 89.8]
Isolated fever present on examination
26.1%
96.2%
66.7%
81.7%
[15.7 – 36.5]
[93.8 – 98.6]
Digestive symptoms
13.0%
62.9%
9.3%
71.3%
[5.1 – 21.0]
[57.2 – 69.4]
QBC
98.6%
99.6%
98.6%
99.6%
  [9.7 – 100]
[98.8 – 100]
   
HRP2
84.0%
98.0%
92.0%
95.0%
(for P. falciparum) [75.4 – 92.7] [96.7 – 99.9]