Table 4.
Statistical value of clinical signs, association of clinical signs and malaria tests (QBC and HRP2-based RDT) for the diagnosis of malaria, according to the results of the thick and thin Giemsa-stained blood films, considered to be the gold standard method (with 95% confidence intervals for sensibility and specificity)
Sensibility | Specificity | Positive predictive value | Negative predictive value | |
---|---|---|---|---|
Isolated fever |
78.3% |
71.3% |
44.3% |
91.9% |
[68.5 – 88.0] |
[65.6 – 77.1] |
|||
Fever present on examination |
31.9% |
85.2% |
38.6% |
81.1% |
[20.9 – 42.9] |
[80.7 – 89.8] |
|||
Isolated fever present on examination |
26.1% |
96.2% |
66.7% |
81.7% |
[15.7 – 36.5] |
[93.8 – 98.6] |
|||
Digestive symptoms |
13.0% |
62.9% |
9.3% |
71.3% |
[5.1 – 21.0] |
[57.2 – 69.4] |
|||
QBC |
98.6% |
99.6% |
98.6% |
99.6% |
[9.7 – 100] |
[98.8 – 100] |
|||
HRP2 |
84.0% |
98.0% |
92.0% |
95.0% |
(for P. falciparum) | [75.4 – 92.7] | [96.7 – 99.9] |