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. 2013 Jul 10;12:69. doi: 10.1186/1475-925X-12-69

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Copyright © 2013 Broomé et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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a-e. Pressure volume loops in left (black) and right (gray) ventricle during stepwise simulation of moderate exercise. (a). Normal resting state. HR 72/min. CO 5.11 l/mint.SAP112/61(79). PAP 24/8(12). (b). Increase in heart rate +100%.HR 144/min. CO 7.08 l/mint.SAP132/86(102). PAP 26/9(14). (c). Increase in right and left ventricular systolic function +50%. HR 144/min. CO 8.41 l/mint SAP153/95(117). PAP 29/9(15). (d). Decrease in systemic arterial resistance. Increase in systemic arterioli diameter +50%. HR 144/min. CO 9.23 l/mint.SAP 86/48(60). PAP 30/9(15). (e). Decrease in pulmonary arterial resistance.Increase in pulmonic arterioli diameter +50%. HR 144/min. CO 10.18 l/mint.SAP 94/50(65). PAP 27/5(13).