Table 2.
Pathological and immunohistochemical findings in duodenal GISTs, and a list of primary antibodies used in diagnosis
| Variable | Dilution, Source of Antibodies | Total | SkF group | non-SkF group | P value |
|---|---|---|---|---|---|
| Number |
|
20 |
12 |
8 |
|
| Tumor size – mm |
|
46.5 ± 63.4 |
23.3 ± 8.2 |
81.2 ± 92.2 |
<0.001 |
| Spindle type cell - no. (%) |
|
13 (65%) |
8 (67%) |
5 (63%) |
0.608 |
| Necrosis - no. (%) |
|
6 (30%) |
0 (0%) |
6 (75%) |
<0.001 |
| Ulceration - no. (%) |
|
15 (75%) |
7 (58%) |
8 (100%) |
0.051 |
| Mitosis - no. per 50 HPF |
|
89.6 ± 233.3 |
0.0 ± 0.0 |
224.0 ± 336.6 |
<0.001 |
| Mib-1 index -% |
1:200, autoclave; MBL |
11.6 ± 17.4 |
1.8 ± 1.2 |
26.3 ± 20.3 |
<0.001 |
| KIT - no. (%) |
1:100, autoclave; Dako |
20 (100%) |
12 (100%) |
8 (100%) |
0.999 |
| CD34 - no. (%) |
1:100, autoclave; Ventana |
14 (70%) |
9 (75%) |
5 (63%) |
0.455 |
| S-100 - no. (%) |
1:1000; Dako |
14 (70%) |
9 (75%) |
5 (63%) |
0.455 |
| α-smooth-muscle actin - no. (%) |
1:200, autoclave; Dako |
14 (70%) |
9 (75%) |
5 (63%) |
0.455 |
| Desmin - no. (%) | 1:40, autoclave; Dako | 11 (55%) | 8 (67%) | 3 (38%) | 0.205 |
Data expressed as mean ± SD, where appropriate.