Table 1.
Specimen collection and testing | If PCR positive @ d28, 42 or 56 | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Day |
0d |
7 |
14 |
21 |
28 |
35 |
42 |
49 |
56 |
|
Number of swabs collected |
4 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
2 |
4-5 |
Culture |
X |
|
|
|
|
|
|
|
|
X |
PCRa |
X |
X |
X |
X |
|
X |
|
X |
|
X |
Chlamydia organism loada |
X |
X |
X |
X |
X |
X |
X |
X |
X |
X |
Genotypea |
X |
X |
X |
X |
X |
X |
X |
X |
X |
X |
Sequencinga |
X |
X |
X |
X |
X |
X |
X |
X |
X |
X |
Y-chromosomea |
|
X |
X |
X |
X |
X |
X |
X |
X |
X |
β-globina |
X |
X |
X |
X |
X |
X |
X |
X |
X |
X |
Test of cureb |
|
|
|
|
X |
|
X |
|
X |
|
Az absorptiona |
|
X |
|
|
|
|
|
|
|
|
Blood |
X |
|
|
|
|
|
|
|
|
X |
Rectal swabc |
|
|
|
|
|
|
|
|
|
X |
Location | Clinice | Clinice | Homef | Homef | Homef | Homef | Homef | Homef | Homef | Clinice |
aProcessed in batches throughout the course of the study.
bChlamydia PCR done in real time to report results back to participants and treat any women diagnosed chlamydia positive.
cIf anal sex reported.
dDay 0 = baseline or at time of recruitment.
eSwabs collected by research nurse and put immediately into the appropriate medium.
fSelf-collected high-vaginal swabs.
Key: X = specimen processed for this experiment, PCR polymerase chain reaction, Az absorption azithromycin absorption, d day.