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. 2013 Aug 23;8(8):e73160. doi: 10.1371/journal.pone.0073160

Figure 3. Influence of HBgGT on the activation of the NF-κB, AP-1 and CREB pathways.

Figure 3

NF-κB, AP-1 and CREB transcriptional activity in transiently transfected HCT116 (A), and DLD-1 and LS174T (B) cells. Recombinant HBgGT (5µg/ml) was added to H. bilis ΔgGT-infected cells and transcriptional activity determined after 24 hours of infection. Results are expressed as mean of relative luciferase activity to renilla of three independent experiments, normalized to the untreated control. *p<0.05, **p<0.005, ***p<0.0005. Asterisks on top of bars indicate significance relative to untreated control; asterisks on bars indicate significance level between indicated conditions.