TABLE 1.
Mouse group | % Parasitized samples (no. parasitized/total no. examined)
|
|||
---|---|---|---|---|
Heart | Liver | Striated muscle | Blood | |
With tissue nestsb | ||||
A/J | 0 (0/24) | 0 (0/24) | 4.8 (1/21) | |
C3H | 13.0 (3/23) | 0 (0/23) | 0 (0/20) | |
With positive LIT culturesc | ||||
A/J | 0 (0/14) | 0 (0/14) | NDd | 28.6 (4/14) |
C3H | 38.5 (5/13) | 0 (0/13) | ND | 38.5 (5/13) |
At the time of sacrifice, all C3H/HePAS and A/J chronically infected mice displayed positive serology for Sylvio X10/4 parasite antigen.
Parasite nests were observed by optical microscopy in tissue sections stained with hematoxylin-eosin.
Tissue parasites were evaluated by culture of tissue homogenate aliquots in LIT medium, as described in Materials and Methods.
ND, not done.