Table 4. Final regression model for coronary artery calcification.
Independent Variable (increment) | lnCAC (n = 434) |
β-Coefficient (95% CI) | |
Age (10 yr. increase) | 0.82 (0.65, 1.0) |
Gender (male vs. female) | 0.70 (0.35, 1.0) |
Lipid-lowering medication | 0.65 (0.31, 1.0) |
Diabetes Status (vs. normal) | |
Impaired fasting glucose | 0.46 (0.06, 0.86) |
Diabetes (untreated) | ns |
Diabetes (treated) | ns |
CD4+ Memory cells (15.2%) | 0.20 (0.03, 0.37) |
Model R2 | 0.21 |
Backward elimination regression was used to develop multivariate models for coronary artery calcification (CAC) level. CAC was analyzed using the ln-agatston score in individuals with a score >0. Independent variables were divided by their standard deviations (shown in parentheses). The candidate starting variables were: age, gender, race/ethnicity, IL-6, BMI, systolic BP, use of BP lowering medication, smoking status, total-cholesterol, HDL-cholesterol, use of lipid lowering medication, type 2 diabetes status, CMV and H. pylori titers, and CD4+ memory cell proportions or, in separate analyses, CD4+ naive cell proportions. Only significant variables (p<0.05) were retained in the final model to obtain the model's R2. ns: non-significant.