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Immunohistochemistry and morphoproteomic studies: SPARC (secreted protein acidic and rich in cysteine) is expressed at 2-3+ in the cytoplasm of the tumor cells. The mammalian target of rapamycin (mTOR) Ser 2448 is expressed up to 2+ in the nuclei of the tumor cells. P-AKT and PDGFR β IHC staining showing an intensity of 2+.
