Figure 1.

Phylogenetic analysis of the 10 mutans streptococci strains compared in this study and their phylogenetic relationship to other Streptococcus species with genomes known before 01/01/2011. a) 16S rRNA phylogenetic tree of Streptococcus species with genomes known before 01/01/2011 (Since the 16S rRNA sequences were almost identical between the different S. mutans strains, only UA159 is shown as representative). b) Phylogenetic tree of mutans streptococci constructed with the core-genome SNPs obtained by PGAP pipeline [11]. All phylogenetic trees were constructed using ClustalX and Phylip by applying the maximum likelihood (ML) method with bootstrap value set to 100. Values beside branches depict ML bootstrap support values. The scale bars in the unit of “substitution/site” are shown below the trees.