Table 6. Altered expression of several mental retardation (MR) genes in TCF4-knockdown cells.

Gene	Disease	OMIM	Inheritance	FC	P value	Reference
TCF4	PTHS	610954	AD	-3.10	2.02 E-05	[9]
MEF2C	Syndromic MR	613443	AD	3.73	1.37 E-05	[50]
UBE3A	AS	105830	imprinted	-1.39	1.56 E-03 *	[59]
ZEB2	MWS	235730	AD	1.48	3.60 E-03 *	[60]
FMR1	Fragile X syndrome	300624	X-linked	1.94	1.51 E-02 **	[61]

Data presented are the fold change and the corrected P value (FDR 0.01) derived from the microarray. *Pass FDR correction of 0.05, **pass FDR correction of 0.1. Abbreviations: PTHS, Pitt-Hopkins syndrome; AS, Angelman Syndrome; MWS, Mowat-Wilson syndrome.