Skip to main content
. Author manuscript; available in PMC: 2015 Jun 5.
Published in final edited form as: Eur J Pharmacol. 2012 Jun 23;732:159–168. doi: 10.1016/j.ejphar.2012.06.001

Table 2.

Summary data for dFBr concentration/responses curves obtained for HS and LS α4β2 nicotinic acetylcholine receptor preparations using HEPES or phosphate ND-96 buffers.

Receptor Buffer pEC50 ± S.E.M. (EC50 μM) Imax (%) pIC50 ± S.E.M. (IC50 μM)
HS HEPES 5.6 ± 0.5 (2.5) 370 4.3 ± 0.8 (50)
LS HEPES 6.2 ± 0.4 (0.63) 260 4.0 ± 1.3 (1 0 0)
HS Phosphate 5.5 ± 0.3 (3.2) 360 4.1 ± 0.1 (79)
LS Phosphate 5.9 ± 1.1 (1.3) 370 5.2 ± 0.6 (6.3)