Figure 3.
Expression of alternative KCC2 transcripts in human DLPFC across the lifespan. Each panel shows the expression pattern of four selected alternative KCC2 transcripts across the lifespan in the human DLPFC: A, AK098371; B, EXON6B; C, EXON2B; D, ΔEXON6. ΔEXON6 shows a pattern different from the other three alternative KCC2 transcripts, as it is highest in the fetus and then declines. The x-axis before birth gestational age is in weeks (wks) and after birth the x-axis shifts to years (yrs). The expression levels on the y-axis were Log2 normalized. Each dot represents an individual subject. The diamonds indicate the best fit curve for lifetime expression.