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. 2013 Aug 20;105(4):899–910. doi: 10.1016/j.bpj.2013.06.046

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© 2013 by the Biophysical Society.

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The radial distribution function of the Aβ peptide with different lipid and sterol components for: (a) the most asymmetric 30%/70% exo/cyto cholesterol distribution with total cholesterol of 40%; (b) the 40%/60% exo/cyto cholesterol distribution with total cholesterol of 40%; (c) the symmetric 50%/50% exo/cyto cholesterol distribution with total cholesterol of 40%; (d) no cholesterol. The symmetric 50%/50% exo/cyto cholesterol distribution with total cholesterol of (e) 20% and (f) 80%, in which the high cholesterol concentration in the membrane is found to be a crystalline ordered phase.