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(A) Effect of time on the uptake of polystyrene microspheres in the jejunum and ileum is shown. The biodistribution of 500-nm MSs 1, 3, and 5 h after local delivery to the jejunum (B) and 1-μm MSs 1, 3, and 5 h after local delivery to the ileum (C) are also shown. D shows quantitative resident time analysis of 500-nm and 1-μm MSs 5 h after oral administration.
