Table 1.
Associations of CD44s expression with clinicopathologic factors
| Characteristic |
CD44s expression |
Pa | ||
|---|---|---|---|---|
|
Total no. of patients |
Negative (%) |
Positive (%) |
||
| Histologic type | .039 | |||
| High-grade serous carcinoma | 376 | 231 (61) | 145 (39) | |
| Low-grade serous carcinoma | 17 | 15 (88) | 2 (12) | |
| Endometrioid adenocarcinoma | 35 | 24 (69) | 11 (31) | |
| Clear cell carcinoma | 16 | 10 (63) | 6 (37) | |
| Transitional cell carcinoma | 11 | 3 (27) | 8 (73) | |
| Other b | 28 | 16 (57) | 12 (43) | |
| FIGO stage | < .001 | |||
| I–II | 51 | 45 (88) | 6 (12) | |
| III–IV | 432 | 254 (59) | 178 (41) | |
| Grade | .013 | |||
| Low | 26 | 22 (85) | 4 (15) | |
| High | 457 | 277 (61) | 180 (39) | |
| Ascites status | .097 | |||
| No | 54 | 39 (72) | 15 (28) | |
| Yes | 338 | 201 (60) | 137 (40) | |
| Unknown | 91 | 59 (65) | 32 (35) | |
| Response to clinical treatment | .059 | |||
| No | 59 | 30 (51) | 29 (49) | |
| Yes | 386 | 249 (65) | 137 (35) | |
| Unknown | 38 | 20 (53) | 18 (47) | |
| Age at diagnosis | .011 | |||
| <60 years | 242 | 136 (56) | 106 (44) | |
| ≥60 years | 241 | 163 (68) | 78 (32) | |
| Serum CA125 level | .378 | |||
| <500 U/ml | 138 | 86 (62) | 52 (38) | |
| ≥500 U/ml | 222 | 127 (57) | 95 (43) | |
| Unknown | 123 | 86 (70) | 37 (30) | |
a
Fisher’s exact test.
b
mucinous adenocarcinoma (five cases), malignant mixed müllerian tumor (ten cases), undifferentiated carcinoma (ten cases), and mixed type carcinoma (three cases).