Table 1. Blood composition and urine pH from control and acidotic rats.
Group | BW (g) | pH urine | Cl− (meq/l) | Na+ (meq/l) | K+ (meq/l) | CO2 (meq/l) | BUN (meq/dl) | SCr (mg/dl) |
---|---|---|---|---|---|---|---|---|
Control, n=7 | 215 ±0.8 | 6.7 ± 0.07 | 122 ±4.7 | 149 ± 1.3 | 3.8 ± 0.3 | 19.2 ± 1.6 | 22.9 ± 1.5 | 0.48 ± 0.1 |
Acidosis (5 days), n=5 | 209 ±6 | 5.9 ± 0.01 | 136 ±2 | 149 ± 1.1 | 2.8 ± 0.3 | 11.2 ± 0.8 | 31.8 ±3.4 | 0.36 ± 0.04 |
P-value | NS | 0.000003 | 0.03 | NS | NS | 0.002 | 0.02 | 0.02 |
Abbreviations: BUN, blood urea nitrogen; BW, body weight; Cr, creatinine; NS, not significant; SCr, serum Cr.
Serum electrolytes, total CO2, Cr, and BUN levels were measured in control rats (water; n=7) or in those subjected to metabolic acidosis (280 mm NH4Cl intake for 5 days; n=5). Values are means ± s.e.