Skip to main content
. Author manuscript; available in PMC: 2014 Jul 5.
Published in final edited form as: J Org Chem. 2013 Jun 25;78(13):6648–6656. doi: 10.1021/jo4009589

Table 3.

Cross-coupling of Potassium Trifluoro(N-methylpyrazolo)borate with Aryl and Heteroaryl Halides

graphic file with name nihms498852u4.jpg
entry aryl halide product % yield
1 graphic file with name nihms498852t29.jpg 3a X = Cl, 56
X = Br, 68
2 graphic file with name nihms498852t30.jpg 3b X = Cl, 81
X = Br, 71
3 graphic file with name nihms498852t31.jpg 3c X = Cl, 76
X = Br, 78
4 graphic file with name nihms498852t32.jpg 3d X = Cl, 60a
X = Br, 45
5 graphic file with name nihms498852t33.jpg 3e X = Cl, 72
X = Br, 68
6 graphic file with name nihms498852t34.jpg 3f X = Cl, 63
X = Br, 82
7 graphic file with name nihms498852t35.jpg 3g 61
8 graphic file with name nihms498852t36.jpg 3h 73
9 graphic file with name nihms498852t37.jpg 3i 58
10 graphic file with name nihms498852t38.jpg 3j 82
11 graphic file with name nihms498852t39.jpg 3k 60
a

3 equiv of KOH used instead.