Table 2.
Summary of ASR values by group
| Group | n | Magnitude (μV)a
|
Onset latency (ms)b
|
||||||
|---|---|---|---|---|---|---|---|---|---|
| 104 dB | 112 dB | 116 dB | P valued | 104 dB | 112 dB | 116 dB | P valued | ||
| Control meanc | 30 | 20.46 (8.09) | 34.22 (10.86) | 47.01 (12.22) | 53.65 (1.99) | 52.82 (1.84) | 52.02 (1.87) | ||
| Baseline | 29 | 15.63 (4.65) | 30.36 (7.56) | 38.29 (8.84) | Reference | 53.95 (3.11) | 51.94 (1.96) | 55.22 (2.61) | Reference |
| Day 30 | 23 | 17.27 (7.39) | 31.73 (10.87) | 47.89 (11.72) | 0.27 | 52.59 (1.91) | 55.63 (2.88) | 48.35 (2.27) | 0.348 |
| Day 90 | 17 | 33.02 (17.21) | 44.17 (20.01) | 60.27 (22.48) | 0.576 | 54.45 (3.98) | 49.92 (2.26) | 51.26 (2.57) | 0.277 |
| Overall P value for Decibel levele <0.0001 | Overall P value for Decibel levele=0.1299 | ||||||||
| Overall P value for days since baselinee=0.5385 | Overall P value for days since baselinee=0.4738 | ||||||||
| Overall P value for smoking statuse=0.7855 | Overall P value for smoking statuse=0.8502 | ||||||||
| Cocaine | |||||||||
| Days abstinent | |||||||||
| 0–4 | 21 | 14.14 (4.29) | 26.20 (7.10) | 38.18 (10.27) | Referencef | 60.05 (4.06) | 52.93 (2.88) | 59.87 (3.71) | Reference |
| 5–10 | 25 | 18.11 (6.92) | 27.39 (7.70) | 33.02 (8.00) | 0.301 | 60.55 (3.85) | 63.88 (3.24) | 64.47 (2.99) | 0.008 |
| 11–18 | 33 | 18.98 (3.81) | 33.36 (6.88) | 44.36 (8.46) | 0.5776 | 59.36 (3.85) | 55.91 (3.42) | 57.76 (3.06) | 0.274 |
| 19–39 | 67 | 22.48 (9.09) | 39.10 (12.95) | 57.26 (15.23) | 0.0151 | 59.88 (3.70) | 57.54 (2.03) | 58.01 (2.23) | 0.403 |
| 40–93 | 50 | 10.73 (3.33) | 22.16 (6.36) | 32.65 (7.59) | 0.0011 | 63.30 (4.88) | 60.42 (2.59) | 62.91 (2.30) | 0.0868 |
| 94–190 | 30 | 9.85 (4.72) | 23.47 (13.21) | 32.14 (15.79) | <0.0001 | 58.77 (5.42) | 56.07 (2.27) | 58.77 (5.42) | 0.224 |
| 191–278 | 15 | 4.70 (1.89) | 11.73 (6.17) | 22.30 (10.11) | 0.011 | 52.38 (6.42) | 63.94 (4.16) | 62.23 (4.24) | 0.8966 |
| >276 | 20 | 4.82 (1.53) | 12.81 (3.23) | 18.22 (5.65) | 0.0006 | 72.36 (7.66) | 64.03 (3.78) | 56.83 (3.62) | 0.1493 |
| Overall P value for Decibel levele <0.0001 | Overall P value for Decibel levele=0.0202 | ||||||||
| Overall P value for Days Cleane<0.0001 | Overall P value for Days Cleane=0.0065 | ||||||||
| Overall P value for interaction between days clean and smoking statuse<0.0001 | |||||||||
a
Mean (SEM) across all session
b
Mean (SEM) across session of block 1
c
Represent the mean (SEM) of three test sessions. Note: one subject’s baseline session data was excluded due to equipment failure
d
Wald Chi-square P value from GEE model comparing each time point to the baseline value while controlling for decibel level and smoking status
e
Overall Wald chi-square P value from GEE model for each effect in the model
f
Wald chi-square P value based on model without interaction with smoking status