Table 2.
Diagnostic Efficiency of Different Algorithms Screening for Pediatric Bipolar Disorder
| Algorithm | Sensitivity | Specificity | Test Positive Rate | Kappa | PPV | Projected PPV (5% prevalence) |
|---|---|---|---|---|---|---|
| FIRM Score 8+ | .28 | .89 | .14 | .18** | .32 | .12 |
| P-MDQ 8+ | .49 | .84 | .21 | .28*** | .49 | .14 |
| CBCL Ext 70+ | .63 | .42 | .59 | .02 | .15 | .05 |
| PGBI-10M 18+ | .19 | .95 | .07 | .18** | .40 | .17 |
|
| ||||||
| FIRM 8+ or P-MDQ 8+ | .58 | .77 | .29 | .26*** | .31 | .07 |
| FIRM 8+ or CBCL 70+ | .65 | .65 | .60 | .03 | .17 | .09 |
| FIRM 8+ or PGBI-10M 18+ | .40 | .40 | .18 | .23*** | .33 | .13 |
Note.
*
p < .05
**
p < .01
***
p < .005; “test positive rate” refers to the percentage of the sample that would “test positive” based on each algorithm. It is also known as the “level” of the test in Kraemer’s (1992) terminology.