Table 2.

Heart rate (HR) and blood pressure during leg cycling (Ex) and post-exercise ischaemia (PEI) for the control, β-adrenergic blockade and parasympathetic blockade conditions

	Experimental phase			P value
	Rest	Ex	PEI	Drug	Phase	Interaction
HR (beats min-1)
Control	66 ± 3	99 ± 2*	77 ± 2*†	<0.001	<0.001	<0.001
β-Block	56 ± 3§	85 ± 3*§	69 ± 2*†
Parasympathetic block	114 ± 3§¶	132 ± 4*§¶	123 ± 5*†§¶
SBP (mmHg)
Control	116 ± 2	132 ± 4*	132 ± 3*	0.656	<0.001	<0.001
β-Block	112 ± 2	123 ± 3*	133 ± 4*†
Parasympathetic block	117 ± 4	127 ± 4*	126 ± 5*
MAP (mmHg)
Control	78 ± 2	84 ± 2*	94 ± 2*†	0.177	<0.001	<0.001
β-Block	78 ± 2	81 ± 2	100 ± 3*†
Parasympathetic block	89 ± 3§¶	88 ± 3	99 ± 4*†
DBP (mmHg)
Control	61 ± 2	62 ± 2	75 ± 2*†	0.041	<0.001	<0.001
β-Block	61 ± 2	61 ± 3	80 ± 3*†
Parasympathetic block	74 ± 3§¶	68 ± 3*	83 ± 4*†

Values represent means (±SEM) at rest (3 min) and last minute of each experimental phase. SBP, systolic blood pressure; MAP, mean arterial pressure; DBP, diastolic blood pressure. P values are derived from ANOVA evaluation of main effects of drug, phase and interaction (drug × phase). *P < 0.05 vs. rest, †P < 0.05 vs. Ex, §P < 0.05 vs. control, ¶P < 0.05 vs. β-blockade.