FIG. 6.

Agar diffusion chemosensitization of S. cerevisiae strains AD/PDR5⁻ and AD/PDR5⁺ to FLC by the deconvoluted combinatorial library pool, subpools, and purified peptides. Strain AD/PDR5⁻ was grown on CSM-ura with agarose in the absence of FLC (A), and strain AD/PDR5⁺ was grown in the absence of FLC (B) or in the presence of FLC at 120 μg ml⁻¹ (C) with DMSO (5 μl; control), the deconvoluted peptide pool, subpools, and HPLC-purified peptides. The agar diffusion chemosensitization assay was conducted as described in Materials and Methods.