TABLE 3.
Chemosensitization of S. cerevisiae AD/PDR5+ to other azole antifungal agents by KN20
| Azole | Concn used for chemosensitization
|
MIC
|
Fold chemosensitization by KN20 (for azole MIC) | ||
|---|---|---|---|---|---|
| KN20 (μM) | Azole (μg ml−1) | KN20 (μM) | Azole (μg ml−1) | ||
| ITC | 20 | 10 | 30 | >64 | >6.4 |
| KTC | 20 | 2.5 | 30 | 40 | 16 |