Table 1.
Sequences or chemical structure and IC50 values of CXCR4 ligands. The IC50 value of DV3 was from the previously published results [12]
Name | Peptide Sequenceα | IC50 (nM) |
---|---|---|
| ||
SDF-1α | KPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQI | 14 |
VARLKNNNRQVCIDPKLKWIQEYLEKALNK | ||
| ||
RCP168 | LGASWHRPDKCCLGYQKRPLPQVLLSSWYPTSQLCSK | 40 |
PGVIFLTKRGRQVCADKSKDWVKKLMQQLPVTAR | ||
| ||
Plerixafor |
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180 |
| ||
DV1 | LGASWHRPDKCCLGYQKRPLP | 236 |
| ||
DV3 | LGASWHRPDK | 440b |
| ||
DV3 Dimer |
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133 |
| ||
DV1-K-(DV3) |
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4 |
D-Amino acids are shown in italics.
The IC50 value of DV3 was from the previously published results [12]