Table 3.
Comparison of Papillary and Follicular Thyroid Cancer in SEER's 9-Registry Database (1980–2009)
| |
Papillary |
Follicular |
|
CI |
|||||
|---|---|---|---|---|---|---|---|---|---|
| n | Rate | SE | n | Rate | SE | Pap/FollIRR | LL | UL | |
| Total | 45,942 | 6.21 | 0.03 | 6410 | 0.88 | 0.01 | 7.07 | 6.91 | 7.24 |
| Sex | |||||||||
| Female | 35,131 | 9.21 | 0.05 | 4563 | 1.19 | 0.02 | 7.77 | 7.56 | 7.97 |
| Male | 10,811 | 3.10 | 0.03 | 1847 | 0.55 | 0.01 | 5.63 | 5.39 | 5.87 |
| Age in years | |||||||||
| 0–9 | 32 | 0.03 | 0.01 | 2 | – | – | – | – | – |
| 10–19 | 1014 | 0.94 | 0.03 | 119 | 0.11 | 0.01 | 8.55 | 7.28 | 10.03 |
| 20–29 | 5572 | 4.73 | 0.06 | 581 | 0.49 | 0.02 | 9.65 | 9.03 | 10.31 |
| 30–39 | 9878 | 8.24 | 0.08 | 1050 | 0.88 | 0.03 | 9.36 | 8.90 | 9.85 |
| 40–49 | 10,586 | 10.17 | 0.10 | 1244 | 1.20 | 0.03 | 8.48 | 8.07 | 8.90 |
| 50–59 | 8827 | 11.14 | 0.12 | 1144 | 1.44 | 0.04 | 7.74 | 7.34 | 8.15 |
| 60–69 | 5761 | 10.18 | 0.13 | 1027 | 1.82 | 0.06 | 5.59 | 5.28 | 5.93 |
| 70–79 | 3171 | 8.15 | 0.14 | 839 | 2.16 | 0.07 | 3.77 | 3.53 | 4.04 |
| +80 years | 1101 | 4.97 | 0.15 | 404 | 1.83 | 0.09 | 2.72 | 2.44 | 3.03 |
| Race/ethnicity | |||||||||
| White | 38,023 | 6.41 | 0.03 | 5140 | 0.87 | 0.01 | 7.37 | 7.21 | 7.53 |
| Black | 2385 | 3.28 | 0.07 | 584 | 0.85 | 0.04 | 3.86 | 3.53 | 4.21 |
| Other | 5091 | 7.32 | 0.1 | 619 | 0.92 | 0.04 | 7.96 | 7.43 | 8.52 |
| Unknown | 443 | – | – | 67 | – | – | – | – | – |
| Registry | |||||||||
| Utah | 4112 | 8.06 | 0.13 | 417 | 0.85 | 0.04 | 9.48 | 8.73 | 10.30 |
| New Mexico | 3472 | 7.34 | 0.13 | 384 | 0.82 | 0.04 | 8.95 | 8.18 | 9.79 |
| Connecticut | 6761 | 6.68 | 0.08 | 887 | 0.87 | 0.03 | 7.68 | 7.24 | 8.14 |
| SF–Oakland | 6135 | 5.14 | 0.07 | 820 | 0.7 | 0.02 | 7.34 | 6.89 | 7.83 |
| Seattle | 6975 | 6.31 | 0.08 | 938 | 0.87 | 0.03 | 7.25 | 6.82 | 7.71 |
| Hawaii | 2779 | 8.16 | 0.16 | 395 | 1.16 | 0.06 | 7.03 | 6.41 | 7.72 |
| Iowa | 4996 | 5.92 | 0.08 | 819 | 0.94 | 0.03 | 6.30 | 5.92 | 6.70 |
| Atlanta | 3946 | 5.38 | 0.09 | 620 | 0.9 | 0.04 | 5.98 | 5.53 | 6.46 |
| Detroit | 6766 | 5.75 | 0.07 | 1130 | 0.97 | 0.03 | 5.93 | 5.61 | 6.27 |
| SEER stage | |||||||||
| Localized | 28,482 | 3.86 | 0.02 | 3348 | 0.46 | 0.01 | 8.39 | 8.16 | 8.62 |
| Regional | 14,939 | 2.00 | 0.02 | 2435 | 0.33 | 0.01 | 6.06 | 5.78 | 6.35 |
| Distant | 1598 | 0.22 | 0.01 | 428 | 0.06 | 0.00 | 3.67 | 3.13 | 4.30 |
| Other/Unknown | 923 | 0.12 | 0.00 | 199 | 0.03 | 0.00 | 4.29 | 4.03 | 4.56 |
| Tumor size (1988–2009) | |||||||||
| 0–1 cm | 13,887 | 2.43 | 0.02 | 296 | 0.05 | 0.00 | 48.60 | 45.59 | 51.81 |
| >1 but ≤2 cm | 10,883 | 1.89 | 0.02 | 835 | 0.15 | 0.01 | 12.60 | 11.82 | 13.43 |
| >2 but ≤4 cm | 8618 | 1.49 | 0.02 | 1839 | 0.32 | 0.01 | 4.66 | 4.40 | 4.93 |
| +4 cm | 6636 | 1.16 | 0.01 | 2087 | 0.37 | 0.01 | 3.14 | 3.01 | 3.26 |
| Other/unknown | 5918 | – | – | 1353 | – | – | – | – | – |
Rates are per 100,000 person years (age-adjusted to the 2000 U.S. standard population). For tumor size, the time period is limited to 1988–2009.